Mediomics抗體 生物標(biāo)志物

Mediomics抗體 生物標(biāo)志物

Mediomics公司于2001年創(chuàng)立于美國(guó)密蘇里州，致力于為科研機(jī)構(gòu)、即時(shí)檢測(cè)、醫(yī)藥企業(yè)以及醫(yī)療和環(huán)境研究市場(chǎng)提供創(chuàng)新的和生物傳感器等產(chǎn)品，其可以簡(jiǎn)單快速的定量檢測(cè)生物學(xué)和臨床相關(guān)的大分子物質(zhì)，包括DNA、生物標(biāo)志物、激素、抗體、細(xì)胞內(nèi)信號(hào)分子、蛋白質(zhì)復(fù)合物、細(xì)菌、真菌和病毒等。
Mediomics目前擁有四個(gè)核心專有技術(shù)：
1. Bridge-It®：一種快速靈敏的DNA-蛋白質(zhì)結(jié)合物檢測(cè)平臺(tái)
       Bridge-It®系列試劑盒可用來(lái)檢測(cè)DNA結(jié)合蛋白及其配體和共調(diào)節(jié)因子。該系列試劑盒基于一個(gè)簡(jiǎn)單的實(shí)驗(yàn)原理：一段針對(duì)已知蛋白的具有序列特異DNA結(jié)合位點(diǎn)的DNA雙鏈被分為兩段，每段含有一個(gè)短的單鏈突出端。這些突出端很短，因此沒有靶蛋白時(shí)他們不會(huì)自發(fā)的重新結(jié)合。當(dāng)靶蛋白出現(xiàn)時(shí)，靶蛋白與完整的DNA序列結(jié)合位點(diǎn)的高親和力使得兩段DNA雙鏈重新結(jié)合。通過(guò)在每段位點(diǎn)加入適當(dāng)?shù)臒晒馓结樉涂梢詸z測(cè)到該結(jié)合。然后用熒光共振能量轉(zhuǎn)移技術(shù)（fluorescence resonance energy transfer，F(xiàn)RET）檢測(cè)熒光信號(hào)的變化來(lái)判斷DNA結(jié)合蛋白或其配體。
該系列試劑盒具有以下特色：

1)      簡(jiǎn)單的混合和測(cè)試方法：只需要混合樣本和反應(yīng)試劑，不需要其他操作技術(shù)。直接檢測(cè)樣本無(wú)需稀釋步驟，只需混合樣本/標(biāo)準(zhǔn)品和反應(yīng)試劑。

2)     快速：孵育30min后即可檢測(cè)熒光信號(hào)。

3)     定量檢測(cè)

4)     可重復(fù)性好：實(shí)驗(yàn)變異性小，避免了抗體或放射性探針帶來(lái)的批次間的差異。

5)     可實(shí)現(xiàn)高通量篩選

2. PINCER®：一種快速的生物傳感器、生物測(cè)定和生物芯片平臺(tái)

PINCER® Assays是一種用于定量檢測(cè)生物樣本中的生物標(biāo)志物、細(xì)胞和病原體濃度的*的技術(shù)。該系列產(chǎn)品分為FRET-PINCER® Assay和TRF-PINCER® Assay兩種，分別使用熒光共振能量轉(zhuǎn)移技術(shù)（fluorescence resonance energy transfer，F(xiàn)RET）和時(shí)間分辨熒光（Time-Resolved Fluorometry，TRF）方法檢測(cè)。其檢測(cè)原理是：帶有熒光探針的抗體由一個(gè)靈活的連接物通過(guò)互補(bǔ)的單鏈DNA突出端與DNA雙鏈化學(xué)結(jié)合，這些突出端使得兩個(gè)DNA片段有結(jié)合的可能性，然而在沒有靶蛋白的情況下，兩個(gè)DNA片段結(jié)合的可能性極小。當(dāng)存在靶蛋白時(shí)，與PINCER試劑結(jié)合的靶蛋白將促使互補(bǔ)DNA單鏈突出端的結(jié)合而形成雙鏈DNA。這種緊密穩(wěn)定的結(jié)合使熒光團(tuán)聚合起來(lái)，發(fā)生熒光共振能量轉(zhuǎn)移。因此，檢測(cè)樣本發(fā)出的熒光能量水平或亮度的變化即可定量靶蛋白的濃度。
PINCER® Assay系列試劑盒的特色：

1)     簡(jiǎn)便：混合樣本/標(biāo)準(zhǔn)品與分析試劑在室溫孵育

2)     快速：孵育30min后檢測(cè)熒光信號(hào)

3)     檢測(cè)范圍廣：直接檢測(cè)樣本，無(wú)需稀釋步驟

4)     兼容性：與大多數(shù)熒光讀數(shù)儀兼容

5)     可實(shí)現(xiàn)高通量篩選

3. 使用創(chuàng)新技術(shù)篩選和研發(fā)可用于科研、臨床診斷和治療的新型高親和力捕獲試劑。

4. 抗血管生成相關(guān)療法

這些技術(shù)已被證實(shí)適于檢測(cè)一系列關(guān)鍵大分子物質(zhì)，包括cAMP、、S-腺苷蛋氨酸、磷酸二酯酶、、胰島素、C肽、白蛋白、C反應(yīng)蛋白、IgG、IgM和大腸桿菌等等。

Mediomics HITR1011-100 hIgG TRF 100 dry ice Store all at -20oC until use ￥2,975.00

Mediomics CHTR1008-100 hCRP TRF 100 dry ice Store all at -20oC until use ￥2,975.00

Mediomics CHTR1008-384 hCRP TRF 384 dry ice Store all at -20oC until use ￥8,500.00

Mediomics CHTR1021-50 hCRP TRF 50 dry ice Store all at -20oC until use ￥3,740.00

Mediomics CHTR1021-96 hCRP TRF 96 dry ice Store all at -20oC until use ￥6,800.00

Mediomics AHTR1016-96 hAlbumin TRF 96 dry ice Store all at -20oC until use ￥6,800.00

Mediomics AHTR1016-50 hAlbumin TRF 50 dry ice Store all at -20oC until use ￥3,740.00

Mediomics AHTR1005-100 hAlbumin TRF 100 dry ice Store all at -20oC until use ￥2,975.00

Mediomics AHTR1005-384 hAlbumin TRF 384 dry ice Store all at -20oC until use ￥8,500.00

Mediomics BTTR-1006-100 Biotin TRF 100 dry ice Store all at -20oC until use ￥2,975.00

Mediomics BTTR-1006-384 Biotin TRF 384 dry ice Store all at -20oC until use ￥8,500.00

Mediomics RI1015-100 rIgG FRET 100 dry ice Store all at -20oC until use ￥2,550.00

Mediomics IH1017-96 hInsulin FRET 96 dry ice Store all at -20oC until use ￥6,375.00

Mediomics RI1015-384 rIgG FRET 384 dry ice Store all at -20oC until use ￥7,650.00

Mediomics IH1017-50 hInsulin FRET 50 dry ice Store all at -20oC until use ￥3,400.00

Mediomics IH1010-100 hInsulin FRET 100 dry ice Store all at -20oC until use ￥2,550.00

Mediomics IH1010-384 hInsulin FRET 384 dry ice Store all at -20oC until use ￥7,650.00

Mediomics CH1021-50 hCRP FRET 50 dry ice Store all at -20oC until use ￥3,400.00

Mediomics CH1021-96 hCRP FRET 96 dry ice Store all at -20oC until use ￥6,375.00

Mediomics IMTR1009-384 mIgM TRF 384 dry ice Store all at -20oC until use ￥8,500.00

Mediomics IMTR1009-100 mIgM TRF 100 dry ice Store all at -20oC until use ￥2,975.00

Mediomics PM-803262-100 µg Recombinant human methionine aminopeptidase-2 dry ice Store at -20oC ￥30,600.00

Mediomics PAB-503208 Anti-recombinant human MetAP-2 (full-length) Polyclonal Antibody dry ice Store at -20oC ￥4,760.00

Mediomics PAB-503209 Anti-hMetAP-2 (C-terminal) Polyclonal Antibody dry ice Store at 4oC ￥4,760.00

Mediomics 122937 10X KRB-IBMX Buffer dry ice Store at -20oC ￥425.00

Mediomics 122934 Bridge-It cAMP 50 dry ice Store all at -20oC until use ￥3,400.00

Mediomics 122935 Bridge-It cAMP 96 dry ice Store all at -20oC until use ￥6,375.00

Mediomics 122939 Bridge-It cAMP 100 dry ice Store all at -20oC until use ￥2,975.00

Mediomics 122938 Bridge-It cAMP 384 dry ice Store all at -20oC until use ￥8,415.00

Mediomics 1-1-1002A Bridge-It L-Tryptophan 100 dry ice Store all at -20oC until use ￥2,975.00

Mediomics 1-1-1002B Bridge-It L-Tryptophan 384 dry ice Store all at -20oC until use ￥8,415.00

Mediomics 1-1-1005A Bridge-It L-MET 50 dry ice Store all at -20oC until use ￥3,400.00

Mediomics 1-1-1005B Bridge-It L-MET 96 dry ice Store all at -20oC until use ￥6,375.00

Mediomics 1-1-1006A Bridge-It L-MET 100 dry ice Store all at -20oC until use ￥2,975.00

Mediomics 1-1-1006B Bridge-It L-MET 384 dry ice Store all at -20oC until use ￥8,415.00

Mediomics 1-1-1003B Bridge-It SAM 96 dry ice Store all at -20oC until use ￥6,375.00

Mediomics 1-1-1003A Bridge-It SAM 50 dry ice Store all at -20oC until use ￥3,400.00

Mediomics 1-1-1004A Bridge-It SAM 100 dry ice Store all at -20oC until use ￥2,975.00

Mediomics 1-1-1004B Bridge-It SAM 384 dry ice Store all at -20oC until use ￥8,415.00

Mediomics PD1016-60 Bridge-It cAMP-PDE 60 dry ice Store all at -20oC until use ￥3,400.00

Mediomics PD1016-96 Bridge-It cAMP-PDE 96 dry ice Store all at -20oC until use ￥6,375.00

Mediomics PD1007-100 Bridge-It cAMP-PDE 100 dry ice Store all at -20oC until use ￥2,975.00

Mediomics PD1007-384 Bridge-It cAMP-PDE 384 dry ice Store all at -20oC until use ￥8,415.00

Mediomics IHTR1010-384 hInsulin TRF 384 dry ice Store all at -20oC until use ￥8,500.00

Mediomics IHTR1010-100 hInsulin TRF 100 dry ice Store all at -20oC until use ￥2,975.00

Mediomics IHTR1017-50 hInsulin TRF 50 dry ice Store all at -20oC until use ￥3,740.00

Mediomics IHTR1017-96 hInsulin TRF 96 dry ice Store all at -20oC until use ￥6,800.00

Mediomics MIGTR1012-384 mIgG TRF 384 dry ice Store all at -20oC until use ￥8,500.00

Mediomics MIGTR1012-200 mIgG TRF 200 dry ice Store all at -20oC until use ￥4,760.00

Mediomics CH1008-384 hCRP FRET 384 dry ice Store all at -20oC until use ￥7,650.00

Mediomics CH1008-100 hCRP FRET 100 dry ice Store all at -20oC until use ￥2,550.00

Mediomics AH1016-96 hAlbumin FRET 96 dry ice Store all at -20oC until use ￥6,375.00

Mediomics AH1016-50 hAlbumin FRET 50 dry ice Store all at -20oC until use ￥3,400.00

Mediomics AH1005-100 hAlbumin FRET 100 dry ice Store all at -20oC until use ￥2,550.00

Mediomics AH1005-384 hAlbumin FRET 384 dry ice Store all at -20oC until use ￥7,650.00

Mediomics TRF-1-1-1006B TR-FRET Bridge-It® L-MET 384 dry ice Store all at -20oC until use ￥8,925.00

Mediomics TRF-1-1-1005B TR-FRET Bridge-It® L-MET 96 dry ice Store all at -20oC until use ￥6,800.00

Mediomics TRF-1-1-1006A TR-FRET Bridge-It® L-MET 100 dry ice Store all at -20oC until use ￥2,975.00

Mediomics TRF-1-1-1005A TR-FRET Bridge-It® L-MET 50 dry ice Store all at -20oC until use ￥3,740.00

Mediomics TRF-1-1-1003B TR-FRET Bridge-It® SAM 96 dry ice Store all at -20oC until use ￥6,800.00

Mediomics TRF-1-1-1003A TR-FRET Bridge-It® SAM 50 dry ice Store all at -20oC until use ￥3,740.00

Mediomics TRF-1-1-1004B TR-FRET Bridge-It® SAM 384 dry ice Store all at -20oC until use ￥8,925.00

Mediomics TRF-1-1-1004A TR-FRET Bridge-It® SAM 100 dry ice Store all at -20oC until use ￥2,975.00

Mediomics TRF-1-1-1001A TR-FRET Bridge-It® L-Tryptophan 50 dry ice Store all at -20oC until use ￥3,740.00

Mediomics TRF-1-1-1001B TR-FRET Bridge-It® L-Tryptophan 96 dry ice Store all at -20oC until use ￥6,800.00

Mediomics TRF-1-1-1002B TR-FRET Bridge-It® L-Tryptophan 384 dry ice Store all at -20oC until use ￥8,925.00

Mediomics TRF-1-1-1002A TR-FRET Bridge-It® L-Tryptophan 100 dry ice Store all at -20oC until use ￥2,975.00

Mediomics 1-1-1001A Bridge-It L-Tryptophan 50 dry ice Store all at -20oC until use ￥3,400.00

Mediomics 1-1-1001B Bridge-It L-Tryptophan 96 dry ice Store all at -20oC until use ￥6,375.00